Systemic Cidofovir in Papillomatosis

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منابع مشابه

Cidofovir injection for recurrent laryngeal papillomatosis.

BACKGROUND Recurrent laryngeal papillomatosis is caused by the human papilloma virus and characterized by multiple exophytic lesions of the vocal tract; it is a benign disease, but one that tends to recur after removal of growths. Due to the nature of the disease, alternative treatment strategies have focused on antiviral injection at lesion sites that eliminate repeated surgical procedures. Th...

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Intralesional cidofovir for recurrent respiratory papillomatosis in children.

OBJECTIVE To assess the potential benefit of intralesional administration of cidofovir, an acyclic nucleoside phosphonate with activity against several DNA viruses, for treating severe respiratory papillomas in pediatric patients. DESIGN Prospective case series. SETTING Tertiary care children's hospitals. PATIENTS Five pediatric patients with severe recurrent respiratory papillomatosis re...

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Efficacy of cidofovir in recurrent juvenile respiratory papillomatosis.

UNLABELLED The efficacy of cidofovir in juvenile recurrent respiratory papillomatosis (JRRP) remains uncertain due to the lack of published case-control studies. AIM To establish factors affecting the progression of JRRP prognosis, and to evaluate cidofovir for eradicating JRRP. STUDY DESIGN Retrospective. METHODS 22 children with JRRP were evaluated at a referral center. All children und...

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Current use of intralesional cidofovir for recurrent respiratory papillomatosis.

OBJECTIVES/HYPOTHESIS The authors sought to define the indications, administration, and adverse events associated with intralesional cidofovir use for recurrent respiratory papillomatosis (RRP). STUDY DESIGN Cross-sectional study. METHODS A 21-question online survey was distributed to 115 selected adult and pediatric laryngeal surgeons internationally. Results were used to draft statements ...

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Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children.

OBJECTIVE To evaluate a stepped-dose protocol for intralesional injection of cidofovir in children with recurrent respiratory papillomatosis (RRP). DESIGN Prospective, nonrandomized case series. SETTING Tertiary care children's hospital. PARTICIPANTS Eleven children undergoing evaluation for RRP from June 1, 2000, through December 31, 2001. INTERVENTION Intralesional injection of cidofo...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2001

ISSN: 1058-4838,1537-6591

DOI: 10.1086/318497